One of the weirdest and rarest medical condition in the history is what doctors termed as Epidermodysplasia Verruciformis (EV), Lewandowsky-Lutz dysplasia, "Tree Man Syndrome."
This is look like a tree bark growing on someone's skin but actually it's a wart-like lesion that exacerbated by exposure to sunlight. Tree Man Syndrome is a lifelong and recessive genetic disorder of the immune system.
These warts are caused of the mutation of EVER1/EVER2 genes. EV is mostly caused by an unusual susceptibility to infection with specific types of human papillomavirus.
Treatments can be non-surgical or surgical. Non-surgical method can be oral and topical retinoids, interferon, immunotherapy, electrodesiccation and cryotherapy, however, these methods are ineffective and give temporary results.
Surgical method is considerably more effective. This treatment executes complete excision and reconstruction of the affected areas in the body of the patient.
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[Source: NCBI]
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